The Patch

A New Approach: The Mosquito-Repellant Patch

The TPI mosquito and insect-repellant patches represent a new technology in the battle against insect-borne diseases. They utilize the medically proven transdermal route of administration which assures greater user compliance and provides continuous 36 hour protection.

Their insect avoidant action employs an effective “cloaking” technology that is in some ways similar to the effect produced by the topically-applied DEET-based insect-avoidants. However, the patches offer a significantly longer (36 hour) efficacy period, their active agent exhibits no toxicity or undesirable side effects and they can be used safely by even the youngest children.

In addition, their application is simple and–most importantly–their effectiveness is not diminished by perspiration, rain, bathing or rub-off.

This permits the patches to offer the full-time “go anywhere, do anything” protection that is required to protect African children and adults against the deadly bite of the anopheles and aedes mosquitoes.

The Protective Action of The Patches

The TPI patches protect against the anopheles mosquito and other biting insects by delivering sustained doses of B-1 thiamin into the system over an extended period.

Although the nutritional value of vitamin B-1 thiamin is common knowledge, what makes it a surprisingly effective mosquito-avoidant is its ability to “mask” the smell of carbon dioxide expelled through breath and perspiration and which are the primary attractants for mosquitoes.

It is well established that mosquitoes are drawn to their subjects by olfactory cues (smell) and can detect their “prey” from as far away as 36 meters. The ability to “mask” the giveaway smell of carbon dioxide by substituting an odor generated by B-1 thiamin is analogous to military “stealth” technology: making the person “invisible” to the mosquito’s “radar”.

It is a simple action but a highly effective one.

The action of the B-1 patches is easy to understand. When the system receives quantities of B-1 beyond its basic nutritional needs, excess B-1 is excreted through the sweat glands. The excreted B-1 has the property of masking the smell of carbon dioxide naturally expelled by breath and perspiration and replacing it with its own smell (which is repugnant to insects).

Over the past three years, the TPI patches have been used and field tested on both children and adults in a wide variety of settings in Liberia and Ghana. These patches are:

  • Licensed by the Ghana Food & Drugs Board, the National Agency for Food & Drug Administration and Control (NAFDAC) of the Republic of Nigeria and the Ministry of Health of the Côte d’Ivoire.

  • In the process of approval by regulatory agencies of other West African nations.

  • Endorsed by the Ghana Schools Health Education Programme for use in the nation’s schools.

  • Endorsed by the Ghana Tourist Board.

  • Marketed in the US, throughout the European Community and the Caribbean.

The TPI anti-mosquito patches are easy to use and will not lose potency or fall off due to perspiring, bathing, swimming or being exposed to rain or abrasion.

The Patches also serve to…

  • Protect against other dreaded insect-borne diseases such as dengue fever (and resultant hemorrhagic fever), lymphatic filariasis and river blindness.

  • Correct a critical diet-related B-1 nutritional deficiency endemic to Africa and Southeast Asia (beri-beri), especially among pregnant women and children.

  • Intervene in the “opportunistic infection” tie-in between malaria and HIV/AIDS. This process makes people infected with HIV/AIDS more prone to contracting severe malaria and persons infected with malaria more susceptible to the HIV virus. Employing the patches as a malaria prophylaxis (prevention measure) in comprehensive HIV/AIDS programs would help disrupt this unfortunate process.